CURRICULUM VITAE

Rudolph Risler, Dr. Sci. Nat.

Senior Research Engineer
University of Washington Medical Center
Department of Radiation Oncology
Div. of Radiation Physics
Box 356043
Seattle, Washington 98195-6043
206 598.4143    FAX:206 598.6218

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Education:

1970, Diploma, Experimental Physics
Federal Institute of Technology (ETH)
Zurich, Switzerland

1974, Dr. Sci. Nat., Experimental Physics
Nuclear Physics Laboratory, ETH
Zurich Switzerland

Research and Professional Ecperience:

1970 - 77 Nuclear Physics Laboratory ETH, Zurich, Switzerland Development, maintenance, operation and documentation of the polarized ion source for the Tandem accelerator. Participation in nuclear physics experiments.

1978 Nuclear Physics Laboratory, University of Washington, Seattle, Washington. Work on several accelerator experiments, development of charge exchange system for a duoplasmatron ion source.

1979 Lockheed Research Laboratory, Palo Alto, California. Fourteen months in Antarctic research station as scientific observer for an upper atmospheric research project. Maintenance and repair of various electronic equipment. Operation of a computer controlled 200 kW VLF radio transmitter.

1980 Nuclear Physics Laboratory, University of Washington, Seattle, Washington. Polarized beam experiment at the Tandem accelerator.

1981 - Present Department of Radiation Oncology, University of Washington, Seattle, Washington. Installation and subsequent operation of the clinical cyclotron used for fast neutron radiotherapy and isotope production. Leader of the Cyclotron Support Group. Accelerator related experimental work. Experimental dosimetry work for Boron Neutron Capture Therapy (BNCT).

Refereed Publications and Patents:

Stelzer, K.J., Laramore, G.E., Risler, R., Wilbur, D.S., Weins, L., Griffin, T.S.: Boron neutron capture enhancement of fast neutron-induced cell kill as a function of fast neutron fraction size. Proc. 7th International Symposium on Neutron Capture Therapy for cancer. B-2:31, 1996.

Laramore, G.E., Risler, R., Griffin, T.W., Wootton, P., Wilbur, D.S.: Fast neutron radiotherapy and boron neutron capture therapy: application to human melanoma test system. Bull. Cancer/Radiother. 83(1): 1S-7S, 1996

Laramore, G.E., Griffin, T.W., Risler, R., Wootton, P., Stelzer, K.J., Wilbur, D.S.: Boron neutron capture (BNC): A mechanism for enhancing tumor cell kill in fast neutron radiotherapy. Proc. 5th International Conference on Applications of Nuclear Techniques, "Neutrons in Research and Industry". Ed. G. Vourvopoulos. SPIE-The International Society for Optical Engineering, Publ. pp 23-26, 1996.

Buchholz, T.A., Laramore, G.E., Stelzer, K.J., Risler, R., Wootton, P., Griffin, T.W.: Boron neutron capture enhanced fast neutron radiotherapy for malignant gliomas and other tumors. J. Neuro-Oncol. 33: 171-178, 1997.

Stelzer, K.J., Laramore, G.E., Risler, R., Wilbur, D.S., Wiens, L., Griffin, T.W.: Boron neutron capture enhancement of fast neutron-induced cell kill as a function of fast neutron fraction size. In Proc. of the 7th International Symposium on Neutron Capture Therapy for Cancer. Eds. B. Larsson, J.D. Crawford and R. Weinreich. Elsevier Scientific. 1997, pp 463-467.

Risler, R., Emery, R., Jacky J., Reid, D.: Present and future operation of the Seattle clinical cyclotron facility. Proceedings of the 15th International Conference on Cyclotrons and their Applications. Eds. E. Baron and M. Lieuvin. Institute of Physics Publishing. 1998, pp. 101-104.

Nigg, D.W., Wemple, C.A., Risler, R., Hartwell, J.K., Harker, Y.D., Laramore, G.E.: Modification of the University of Washington neutron therapy facility for optimization of neutron capture enhanced fast neutron therapy. Med. Phys. 27 (2), 2000, pp. 359-367.

Risler, R., Diaz, A.Z., Emery, R., Jacky, J., Laramore, G.E., Reid, D.: Status Report of the Clinical Cyclotron Facility in Seattle. Proceedings of the 16th International Conference on Cyclotrons and Their Applications. Editor F. Marti, American Institute of Physics Conference Proceedings, Vol 600, 2001, pp 136-138.